Hepatic Mitochondrial Prooxidant and Antioxidant Status in Ethanol-Induced Liver Injury in Rats.
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چکیده
منابع مشابه
Hepatic mitochondrial prooxidant and antioxidant status in ethanol-induced liver injury in rats.
In this study, prooxidant and antioxidant status in liver homogenates and their mitochondrial fractions were investigated in both chronic and chronic plus acute ethanol-treated rats. Increases in serum transaminase activities, as well as increases in total lipid, triglyceride, malondialdehyde (MDA) and diene conjugate (DC) levels and decreases in glutathione (GSH), vitamin E and vitamin C level...
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Whereas both ethanol and gut ischemia/reperfusion (I/R) are known to alter hepatic microvascular function, little is known about the influence of ethanol consumption on the hepatic microvascular responses to I/R. The objective of this study was to determine whether acute ethanol administration exacerbates the hepatic microvascular dysfunction induced by gut I/R. Rats were exposed to gut ischemi...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2002
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.25.1482